Search on: HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS 
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Descriptor English:   Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels 
Descriptor Spanish:   Canales Regulados por Nucleótidos Cíclicos Activados por Hiperpolarización 
Descriptor Portuguese:   Canais Disparados por Nucleotídeos Cíclicos Ativados por Hiperpolarização 
Synonyms English:   Hyperpolarization Cyclic-Nucleotide Gated Ion Channels  
Tree Number:   D12.776.157.530.400.368
D12.776.543.550.425.476
D12.776.543.585.400.476
Definition English:   A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55318 
Unique Identifier:   D064428 

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